RESEARCH:
DANDELION LEAF EXTRACT BLOCKS SPIKE
PROTEINS FROM BINDING TO THE ACE2 CELL SURFACE RECEPTOR
-
BLACK SEED AND DANDELION LEAF EXTRACT BLOCK SPIKE
PROTEIN FROM BINDING TO ACE-2 RECEPTORS
- Dandelion extract
inhibits SARS-CoV-2 in vitro
-
Natural molecular
compounds that block spike proteins from binding to ACE2 receptors.
Bioactive chemical components;
·
Taraxerol – (
Dandelion )
·
Withanolide
·
Glycyrrhizin
·
Nigellidine
·
Nobiletin
·
Neohesperidin, a derivative of hesperetin, is a flavanone glycoside also found in citrus
fruits.
·
W. Somnifera
·
Daturaolone
·
Punicalagin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651333/
https://www.biorxiv.org/content/10.1101/2021.03.19.435959v1.full
`
As vaccines weaken
herd immunity, natural herbs promise true prevention, more substantial immunity
The engineered spike
proteins from SARS-CoV-2 can be STOPPED by a common “weed” that is exterminated
from lawns every year. A German university study found that the common
dandelion (Taraxacum officinale) can block spike proteins from binding to the
ACE2 cell surface receptors in human lung and kidney cells. The water-based
dandelion extract, taken from the plant’s dried leaves, was effective against
spike protein D614 and a host of mutant strains, including D614G, N501Y, K417N
and E484K.
The researchers used
high molecular weight compounds taken from a water-based dandelion extract and
put them to the test in human HEK293-hACE2 kidney and A549-hACE2-TMPRSS2 lung
cells. The dandelion blocked the protein-to-protein interactions between the S1
sub unit of the spike protein and the human ACE2 cell
surface receptor. This effect was also true against the spike protein mutations
from the predominant variants in circulation, including the United Kingdom
(B.1.1.7), South African (B.1.351) and Brazilian (P.1) variant.
Other natural
compounds have been investigated using molecular docking studies. Nobiletin is
a flavonoid isolated from citrus peels. Neohesperidin,
a derivative of hesperetin, is a flavanone glycoside
also found in citrus fruits. Glycyrrhizin is a molecular compound extracted
from licorice root. All three of these natural substances also block spike
proteins from binding to ACE2 receptors. Hydroalcoholic pomegranate peel
extract blocks the spike protein at the ACE2 receptor with 74 percent efficacy.
When its principal constituents were tested separately, punicalagin was 64
percent effective, and ellagic acid was 36% percent effective.
These natural
compounds (along with dandelion extract) can be readily mass produced, combined
and deployed as preventative medicine for all future spike protein variants.
These herbs are generally recognized as safe, and there are no known cases of
overdose with dandelion leaf extract. According to the European Scientific
Cooperative on Phytotherapy, the recommended dosage of dandelion leaf is 4–10
grams steeped in hot water, up to three times per day.
BLACK SEED AND
DANDELION LEAF EXTRACT BLOCK SPIKE PROTEIN FROM BINDING TO ACE-2 RECEPTORS
https://getbetterwellness.com/blockspike/
Dandelion extract
inhibits SARS-CoV-2 in vitro
https://www.news-medical.net/news/20210323/Dandelion-extract-inhibits-SARS-CoV-2-in-vitro.aspx
Spike protein neutralize and detox
https://www.mtnmusenews.com/post/spike-protein-neutralize-and-detox
Study title: Common
dandelion (Taraxacum officinale) efficiently blocks the interaction between
ACE2 cell surface receptor and SARS-CoV-2 spike protein D614, mutants D614G,
N501Y, K417N and E484K in vitro https://doi.org/10.1101/2021.03.19.435959
BLACK SEED
Study: Nigellidine (N. sativa) bind to viral spike/active-sites of
ACE1/2, AT1/2 to prevent COVID-19 induced vaso-tumult/vascular-damage/comorbidity
Nigella sativa, also
known as black seed or black cumin, binds to ACE2 receptors in the lungs,
potentially stopping spike protein particles from inducing inflammation and
vascular damage.
Nigellidine is a key-component of Nigella Sativa L. Another study reported, “It
might have great protective role during post infective secondary disorder of
the peripheral vasculature namely cardiac and renal systems. In most of the
instances patients die due to this organ dysfunction/failure in COVID-19
infection.”
BLACK SEED AND
DANDELION LEAF EXTRACT BLOCK SPIKE PROTEIN FROM BINDING TO ACE-2 RECEPTORS
https://getbetterwellness.com/blockspike/
Common dandelion
(Taraxacum officinale) efficiently blocks the interaction between ACE2 cell
surface receptor and SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N
and E484K in vitro
https://www.biorxiv.org/content/10.1101/2021.03.19.435959v1.article-info
The plant contains a
wide array of phytochemicals including
terpenes
(sesquiterpene lactones such as taraxinic acid and
triterpenes), phenolic compounds
(phenolic
acids, flavonoids, and coumarins) and also polysaccharides (14). The
predominant
phenolic compound was
found to be chicoric acid (dicaffeoyltartaric
acid). The other were
mono- and dicaffeoylquinic acids, tartaric acid derivatives, flavone
and flavonol glycosides.
The roots, in
addition to these compound classes, contain high amounts of inulin (15).
Our research was
conducted using water-based extracts from plant leaves. We found that leaf
extracts efficiently blocked spike
protein or its mutant
forms to the ACE2 receptor, used in either pre- or post-incubation, and
that high molecular
weight compounds account for this effect.
bioactive compounds
were mostly present in the HMW fraction
COMPOUNDS THAT BLOCK
SPIKE PROTEINS ; glycyrrhizin, nobiletin, and neohesperidin,
ACE2 binding falls
partially within the RBD contact region and thus, these have been proposed
to additionally block
spike binding to ACE2 (20).
The same accounts for
synthetic ACE2 inhibitors, such as N-(2-aminoethyl)-1 aziridine-ethanamine (NAAE) (21).
In contrast, the lipoglycopeptide
antibiotic dalbavancin has now been identified as both, ACE2 binder and
SARS-CoV-2 spike-ACE2
inhibitor (22); SARS-CoV-2 infection was effectively inhibited in both
mouse and rhesus
macaque models by this compound.
Also, for a
hydroalcoholic pomegranate peel extract, blocking of spike-ACE2 interaction was
shown at 74%, for its main
constituents
punicalagin at 64%, and ellagic acid at 36%.
Molecular weight
fractionation from plant extracts
Extracts from dried
plant leaves were prepared by adding bidistilled
water (5 ml) to plant
material (500 mg
each). The samples were incubated in the dark at room temperature (RT) for
60 min, followed by
centrifugation at 16.000 g for 3 min. The supernatants were collected and
membrane filtrated
(0.45 µm), resulting in the extracts. Aliquots were freeze dried for 48h to
determine their yield
by weight. The extracts were then further separated in a high molecular
weight (HMW) and low
molecular weight (LMW) fraction, using a centrifugation tube with an
insert containing a
molecular weight cut-off filter (5 kDa, Sartorius Stedim Biotech, Goettingen,
Germany). Each HMW
fraction was purified by flushing with 20 ml of water, yielding the HMW
fractions, as well as
LMW. The fractions were freeze dried, their yield
determined by weight
and stored at -20°C
until use
https://www.biorxiv.org/content/10.1101/2021.03.19.435959v1.full.pdf
Natural compounds
could yield effective and safe antiviral therapeutics and have been reported
for many decades. Compounds like glycyrrhizin show inhibition of the ACE2
receptor. However, they may also produce incomplete occlusion of the RBD
contact motif, thus preventing spike-ACE2 binding.
Synthetic inhibitors
of ACE2 binding like N-(2-aminoethyl)-1 aziridine-ethanamine
(NAAE) also show the same behavior. The antibiotic dalbavancin both binds ACE2
and inhibits spike-ACE2 binding, and effectively inhibited infection by this
virus in mouse and non-human primate models.
Pomegranate peel
extract also showed 74% inhibition of this interaction, and
blocking of viral entry into human kidney cells in culture.
Dandelion extract
moves beyond this, with potent inhibition of spike-ACE2 binding, confirmed by
inhibition of ACE2-cell surface binding in two different human cell lines.
https://www.news-medical.net/news/20210323/Dandelion-extract-inhibits-SARS-CoV-2-in-vitro.aspx
3. Nutritional,
chemical, and biological properties of dandelion
Dandelion includes
potential bioactive components such as sesquiterpene lactones, taraxasterol (TS), taraxerol,
chlorogenic acid (CGA), and CRA. These components are non-toxic and can be
exploited for their potentially anti-inflammatory, anti-oxidative,
anti-rheumatic, and chloretic properties
Tandem liquid
chromatography and mass spectrometry analysis of dandelion have revealed rich sources
of β-carotene, which protects cells from oxidation and cellular damage
[29]. Recently, biochemical analysis identified chicoric
acid (CRA) as the most abundant component of dandelion, with a polyphenolic
amount of 34.08 ± 1.65 g/kg in Taraxacum officinale leaves and stems [30-32].
The concentration of polyphenols is higher in flowers and leaves than in stems
[33]. There is also considerable seasonal variation; methylsterols
are highly present in the winter, while sitosterol and cycloartenol esters are
more prevalent during periods of extensive sun exposure [34].
The roots of
dandelion contain carbohydrates (e.g. inulin),
carotenoids (e.g. lutein), fatty acids (e.g. myristic acid), minerals, sugars
(e.g. glucose, fructose, and sucrose), choline vitamins, mucilage, and pectin.
Up to 45% of the roots consist of inulin, a complex carbohydrate
(fructo-oligosaccharides) with many beneficial effects such as the elimination
of pathogens in the gastrointestinal tract, and repression of obesity, cancer,
and osteoporosis [35]. Besides its use as a coffee substitute and flavor
enhancer in drinks, the leaf extracts are known to be effective against obesity
and cardiovascular disease [36].
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553762/
BLACK SEED (nigellidine) Nigella sativa L. (Black Cumin): A Promising
Natural Remedy ...https://www.hindawi.com › journals › ecam
by EM Yimer · Cited by 158 — Amongst different active constituents
reported so far, thymoquinone found as major ... and indazole class of
alkaloids: nigellidine, nigellicine
[28.
https://www.greenmedinfo.com/blog/black-seed-remedy-everything-death
2.3. Ligand structure
retrieval and modification
The ligand molecule, nigellidine is a rare indazole-type alkaloid also known as
6,7,8,9-Tetrahydro-1-hydroxy-11-(4-hydroxyphenyl)-3-methylpyridazino[1,2-a]indazol-5-ium inner salt, 9CI. It contains three benzene ring attached through a pentose structure. The molecular
formula and weight were C18H18N2O2 and 294.3 g/mol. The canonical smile was CC1
= CC(=O)C2 = C(N3CCCCN3C2 = C1)C4 = CC=C(C=C4)O. The three dimensional (3D) structure of nigellidine
with PubChem ID of 136,828,302 was retrieved from PubChem chemical structure
database (https://pubchem.ncbi.nlm.nih.gov/) in SDF
format. The retrieved SDF format was saved in PDB format using Pymol.
In silico Nigellidine (N. sativa) bind to viral spike/active-sites of
ACE1/2, AT1/2 to prevent COVID-19 induced vaso-tumult/vascular-damage/comorbidity
Nigellidine strongly binds to the spike-protein at the
hinge-region/active-site-opening which may hamper proper-binding of nCoV2-ACE2
surface. Nigellidine effectively binds in the
Angiotensin- II binding-site/entry-pocket (−7.54 kcal/mol, −211.76,
Atomic-Contact-Energy; ACE-value) of ACE2 (Ki 8.68 and 8.3 μmol)
in comparison to known-binder EGCG (−4.53) and Theaflavin-di-gallate
(−2.85). Nigellidine showed strong-binding (Ki,
50.93 μmol/binding-energy −5.48 kcal/mol)
to mono/multi-meric ACE1. Moreover, it binds
Angiotensin-receptors, AT1/AT2 (Ki, 42.79/14.22 μmol,
binding-energy, −5.96/−6.61 kcal/mol) at active-sites,
respectively. This article reports the novel binding of nigellidine
and subsequent blockage of angiotensin-binding proteins. The ACEs-blocking
could restore Angiotensin-level, restrict vaso-turbulence
in Covid patients and receptor-blocking might stop inflammatory/vascular
impairment. Nigellidine may slowdown the vaso-fluctuations due to Angiotensin-deregulations in Covid
patients. Angiotensin II-ACE2 binding (ACE-value −294.81) is more
favorable than nigellidine-ACE2. Conversely, nigellidine-ACE1 binding-energy/Ki
is lower than nigellidine-ACE2 values indicating a balanced-state between
constriction-dilatation. Moreover, nigellidine binds
to the viral-spike, closer-proximity to its ACE2 binding-domain. Taken
together, Covid patients/elderly-patients, comorbid-patients (with
hypertensive/diabetic/cardiac/renal-impairment, counting >80% of
non-survivors) could be greatly benefited.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7970800/
https://www.biorxiv.org/content/10.1101/2021.03.19.435959v1
https://getbetterwellness.com/blockspike/
What chemicals are
in dandelions?
The anti-diabetic
properties of dandelion are attributed to bioactive chemical components; these
include chicoric acid, taraxasterol (TS), chlorogenic acid, and sesquiterpene
lactones.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553762/
Occurrence
of taraxerol and taraxasterol
in medicinal plants
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441157/
Traditional
medicinal plants against replication, maturation and
transmission targets of SARS-CoV-2: computational investigation
The infectious
pandemic COVID-19 has emerged as a massive threat to humankind. The main
challenges are to control the spread of the disease, developing immunity as the
preventive as well as prophylactic, and discovering therapeutics in a feasible
time. Nature has always blessed us with plentiful remedies like herbs and
medicinal plants for numerous ailments. Therefore, the virtual screening based
on molecular docking was executed to identify potential bioactives
from medicinal plants as effective inhibitors of Mpro, S-protein and ACE2. We found many bioactives
from the medicinal plants have shown either comparable or better binding
affinity with targets of SARS-CoV-2 with desirable pharmacological properties
over the standard drugs. Further, we also observed that the selected bioactives have better intestinal and GI absorptions and
lower toxicity than the standard drugs used. Therefore, these selected bioactives may further be developed as pharmacological
inhibitors against SARS-CoV-2 target proteins involved in viral replication, propagation and transmission. Among them, taraxerol from Clerodendrum has shown potential anti-viral activities with
desirable pharmacological features (Sharma & Zafar, 2015; Verma & Baranwal, 1983). Further, withanolide A from Withania somnifera has shown the highest binding affinity with S-protein
and ACE-2 receptor. The active constituents of ayurvedic herb W. somnifera have shown promising anti-influenza properties by
targeting neuraminidase of H1N1 influenza (Cai et al., 2015). AYUSH Ministry of Health, India, has further recommended
the use of the aqueous extract of this plant as a preventive and prophylactic
for treating COVID-19. Withametelin, from the Datura innoxia plant, has shown a better binding affinity against Mpro, S-protein and ACE2. However, the pharmacological analysis
revealed its toxicity to health. Instead, daturaolone,
another compound from D. innoxia, have shown lower toxicity and higher HIA with potent
anti-viral and anti-inflammatory activities. Overall, the selected medicinal
plant bioactives can be further developed and assessed
as phytoformulations against SARS-CoV-2 infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651333/
Phytotherapy for treatment of
cytokine storm in COVID-19
Table 1: Traditional
medicines possessing anti-inflammatory and anti-viral properties.
|
Phytotherapeutic agents |
Common names |
Family |
Biologically active components |
Pharmacological activities |
Predicted targets in COVID-19 |
Tissue protective activities |
Ref. |
|
Commiphora wightii |
Gugal, Guggul, Indian Bdellium |
Burseraceae |
Guggulsteron, lignans, ketosterols,
flavanones, guggulipid |
Anti-inflammatory
(↓ IL-1β, IL-6, TNF-α), Anti-diabetic, Anti-arthritic, Anti-oxidant, Anti-bronchitis, Anti-viral |
Cytokine storm (IL-1β,
IL-6, TNF-α) |
Neuroprotective,
Cardioprotective, Hepatoprotective, Nephroprotective, Lung protective |
[37] |
|
Salvia officinalis |
Sage |
Lamiaceae |
Alkaloids, phenolic compounds,
steroids polyacetylen, essential oils |
Anti-inflammatory
(↓ IL-1β, IL-6), Anti-cancer, Anti-diabetic, Anti-microbial, Anti-oxidant |
Cytokine storm (IL-1β,
IL-6) |
Neuroprotective,
Cardioprotective, Lung protective |
[38] |
|
Foeniculum vulgre |
Fennel |
Apiaceae |
Coumarins |
Anti-inflammatory
(↓ IL-17), Anti-oxidant |
Inflammatory cytokine (IL-17) |
Lung protective, Skin
protective |
|
|
Mentha balsamea |
Peppermint |
Lamiaceae |
Ursolic acid (triterpenoid compound),
phenolic acids (rosmarinic and caffeic acids),
flavones, flavanones |
Anti-inflammatory
(↓ IL-1β, IL-6, TNF-α), Anti-viral, Anti-oxidant,
Anti-microbial, anti-carcinogenic |
Cytokine storm (IL-1β,
IL-6, TNF-α) |
Skin protective, Improve lung
function |
|
|
Salvia rosmarinus |
Rosemary |
Lamiaceae |
Carnosic acid, Carnosol, |
Anti-inflammatory
(↓ IL-1β, ↓ NF-kB pathway, iNOS), Anti-oxidant,
Anti-osteoporotic, Anti-carcinogenic |
IL-1β, iNOS
in alveolar macrophages, NF-kB pathway |
Lung protective,
Neuroprotective |
|
|
Echinacea purpurea |
Cone flower |
Asteraceae |
Phylloxanthobilins (tetrapyrrolic compounds),
caffeic acids |
Anti-inflammatory,
Anti-bacterial, Anti-oxidant, Anti-Diabetic, Treat
upper respiratory illness, Common cold, Anti-viral, Immunomodulatory
properties (↑ CD4+ and CD8+ T cells) |
Lymphopenia (Increased
CD4+ and CD8+ T cells) |
Lung protective,
Hepatoprotective, Neuroprotective |
|
|
Sambucus nigra |
Elderberry |
Adoxaceae |
Phenolic acids, flavonols, flavonoids, Total phenols |
Anti-inflammatory
(↓ IL-1β, IL-6, TNF-α, COX2, iNOS),
Anti-viral, Treat upper respiratory illness, Anti-microbial, Anti-pyretic,
diuretic agent, Anti-diabetic, Anti-oxidant
properties |
Cytokine storm (IL-1β,
IL-6, TNF-α), iNOS and COX-2 in alveolar
macrophages |
Lung protective,
Hepatoprotective, Nephroprotective |
|
|
Panax ginseng |
Man-root |
Araliaceae |
Ginsenosides, Panax notoginseng saponin (PNS) |
Immunomodulatory properties
(↑humoral and cell mediated immunity), Anti-inflammatory (↓IL-8,
IL-6; inhibits NF-kB signalling pathway) Anti-diabetic, Anti-neurotoxic,
Anti-angiopathy |
Cytokine storm (IL-1β,
IL-6, IL-8, TNF-α), NF-kB pathway |
Neuroprotective, Myocardial
protection, Hepatoprotective, Intestinal protection, Lung protective |
|
|
Taraxacum officinale |
Dandelion |
Asteraceae |
Polysaccharide, Taraxasterol |
Anti-inflammatory
(↓ IL-1β, IL-6, TNF-α), Ameliorates colitis
(↓IL-6/STAT3 pathway), Anti-arthritic, Anti-viral |
Cytokine storm (IL-1β,
IL-6, IL-8, TNF-α), NF-kB pathway, IL-6/STAT3 pathway |
Hepatoprotective, Lung
protective, Neuroprotective, Nephroprotective |
|
|
Tanacetum vulgare |
Tansy |
Asteraceae |
Flavonoids |
Anti-inflammatory (↓iNOS and cytokine induced neutrophil chemo attractants),
Anti-microbial , Anti-viral |
Cytokine storm (IL-1β,
IL-6, IL-8, TNF-α), iNOS |
Nephroprotective,
Neuroprotective |
Table 2: Clinical
trials of natural compounds for COVID-19 management and treatment.
|
Drug |
Composition |
Clinical trial phase/type of
study/No. of participants |
Mechanism of action |
Reference identifier |
|
ArtemiC (Micellar formulation) |
Artemisinin (6 mg), Curcumin
(20 mg), Frankincense (15 mg), Vitamin C (60 mg) |
Phase II/ To evaluate the
safety and efficacy of ArtemiC on patients
diagnosed with COVID-19/50 P |
Diminish IL-6 and TNF-α
levels |
NCT04382040 |
|
Previfenon® |
Epigallocatechin-3-Gallate
(EGCG) (250 mg) |
Phase II/ To determine the
efficacy of Previfenon® (EGCG) to prevent
COVID-19/524 P |
Exhibits anti-viral
chemoprophylaxis of COVID-19 |
NCT04446065 |
|
Guduchi Ghan
Vati |
Giloy (500 mg) |
NA/ To evaluate the safety and
efficacy of Guduchi Ghan Vati for COVID-19 asymptomatic patients/18-75 years age |
Immunomodulatory potential |
NCT04480398 |
|
Gargles (Mouthwash) |
Neem |
NA/ To reduce intraoral viral
load in COVID-19 infected patients/50 P |
Anti-viral |
NCT04341688 |
|
Omega 3 Viruxide |
Neem oil & Wort oil |
NA/ To study the viruxal oral and nasal spray for treating the symptoms of
COVID-19/128 P |
Reduce symptoms associated with
COVID-19 infection |
NCT04357990 |
|
Nigella sativa (Black Cumin) |
Black seed (500 mg) |
Phase II/ To study Nigella
sativa As a treatment option for patients having
upper respiratory infection caused by SARS-CoV-2/200 P |
NA |
NCT04401202 |
|
Nigella sativa (HNS-COVID-PK) |
Cumin seed powder (1 gm) |
Phase III / Role of honey and
Nigella sativa in the management of COVID-19/ 30 P |
NA |
NCT04347382 |
|
Traditional Chinese medicine |
NA |
Phase III/ To evaluate the
safety and efficacy of TCM as an adjuvant for the patients with SARS-CoV-2
COVID-19/50 P |
NA |
NCT04323332 |
|
Individualized Ayurveda |
Ginger/Turmeric/Honey/Lemon |
NA/ Ayurveda self-management
for flu like symptoms during the COVID-19 outbreak/18-6 years age |
—- |
NCT04345549 |
|
NA* denotes Not Available at
clinical trial government site (https://clinicaltrials.gov/). |
||||
https://www.fbscience.com/Landmark/articles/10.52586/4924
https://www.fbscience.com/Landmark/articles/pdf/Landmark4924.pdf
Virtual screening of plant-derived compounds against SARS-CoV-2
viral proteins using computational tools.
https://europepmc.org/article/med/33794459
Prior to discovery of
these new compounds this was the Nutrition Protocol to Prevent Damage from
Spike Protein and Derivatives due to Injection and to Protect from Spike
Protein Shedding:
•Coated Silver (1-6
drops per day, depending on degree of exposure) (Coated silver blocks the
protein on the spikes from entering the cell. sulfur on the spike
protein.
• Zinc (30-80mg per
day depending on immunological pressure)
• Vitamin D3* (10,000
IU’s per day)
• Lypospheric
Vitamin C (30ml, twice daily)*
• Quercetin (500-1000
mg, twice daily)*
• Iodine* (dosage
depends on brand, more is not better. Iodine is a product you have to start with small dosages and build up over time.
• PQQ* (20-40 mg per
day)
Shikimate Main
Sources:
• Pine Needle Tea for
shikimic acid or shikimate (from green edible pine needles) There are toxic
pine needles, be careful! When drinking pine needle tea, drink the oil/resin
that accumulates too! Shikimate, shikimic acid and their derivatives possess:
cancer fighting, antiviral, antimicrobial, anticoagulant and antithrombotic
properties.
• Fennel and/or Star
Anise Tea: These are also an excellent source of shikimate or shikimic acid
(which is known to neutralize the spike protein)
• C60 (1-3 droppersfull per day): One of the issues we are seeing with
those who have been injected is disturbances in their energetic field
(magnetism) and hot spots of inflammation. C60 is a rich-source of electrons
and acts like a fire extinguisher to inflammation and simultaneously (because it bio-distributes throughout the body) drives a
normalization of electron flow throughout the body. In this category, we offer
two products, the traditional C60 product* is made by yours truly and the C60 SuperConcentrate* is made by a carbon scientist friend of
mine and contains a higher concentration of electrons.
• Charcoal (2-4
capsules a day): Charcoal is the pre-eminent detoxifier and when taken on an
empty stomach, works its way down into the intestines and activates a blood
purification process known as “interstitial dialysis”. Our Kohlbitr*
product is the premier activated coconut charcoal in the world and we also now
offer the more gentle birch charcoal.*
•Citrus fruit
(especially blood oranges, due to their high hesperidin content — hesperidin is
a chalcone like quercetin that deactivates spike protein)
Peppermint (very high
in hesperidin)
• Superherbs
to help disable spike protein:
Schizandra Berry*
(high in shikimate)
Triphala formulations: In Sanskrit, the word Triphala
means "three fruits”: a combination of Indian gooseberry (Emblica officinalis), black myrobalan (Terminalia chebula) and belleric myrobalan
(Terminalia belerica). The terminalia fruits are rich
in shikimate.
St. John’s Wort
(shikimate is found throughout the entire plant and in the flowers)
Comfrey Leaf (rich in
shikimate)
Feverfew (leaves and
flowers are rich in shikimate)
Gingko Biloba Leaf
(rich in shikimate)
GiantHyssop or Horsemint (Agastache urtifolia) (rich in
shikimate)
LiquidAmbar (Sweet Gum tree) A tea of the spiky seed pods is rich in shikimate.
•Foods: Carrots and
Carrot Juice (rich in Shikimate)
Dandelion Leaf
(Common dandelion (Taraxacum officinale) efficiently blocks the interaction
between ACE2 cell surface receptor and spike protein D614, mutants D614G,
N501Y, K417N and E484K in vitro)
•Plant Sprouts:
Wheatgrass and
Wheatgrass Juice (the young blades are high in shikimate)
Legume family beans
that are generally considered to be rich in shikimate. I have found testing of
5 sprouts and all were rich in shikimate: red kidney bean (Phaseolus vulgaris),
moth bean (Vigna aconitifolia), soy
bean (Glycine max), mung bean (Vigna radiata) and alfalfa (Medicago
saliva).
https://www.mtnmusenews.com/post/spike-protein-neutralize-and-detox